de·spite/dɪ`spaɪt; dɪˈspaɪt/ prep 1 used to say that something is true, although something else you say seems to make it unlikely; in spite of (SPITE) 尽管，不管: She still loved him despite the way he had treated her. 尽管他曾那个样子对待她，可她还是爱他。 2 despite yourself although you did not intend to 不由自主: He smiled at the little girl despite himself. 他不由得对那个小女孩笑了。